Not recommended in psychotic or severely depressed patients. Not to be used in ambulatory patients suspected of having psychotic tendencies. Epileptic patients; avoid abrupt w/drawal of diazepam. Addiction-prone individuals; may precipitate acute w/drawal symptoms including convulsions w/ abrupt cessation of large doses of diazepam after prolonged periods; gradually discontinue use. Carefully consider use when combined w/ other psychotropic agents (eg, phenothiazines, barbiturates, MAOIs & other antidepressants). Simultaneous ingestion of alcohol & other CNS depressants during therapy. May affect mental alertness & physical coordination. Renal & hepatic impairment. Advise periodic blood counts & LFTs if administered for protracted periods. Elderly & debilitated patients or those w/ organic brain disorders.
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